I have zero experience with E85 in SyTy, but I know the volume of fuel required is much greater than gasoline. The E85 cars I've seen have up-sized everything. Lines, pick-ups, fuel rails, injector sizes, remote regulators, pumps. Everything gets changed.
In the meantime,for a streetable SyTy, run a Walbro 255HP which has been the standard among SyTy enthusiasts for 25 years. No Drama.